Systems and methods for simultaneously protecting software components (150) installed on a computer system (102) against malware. The methods involve executing a first end user application (3181, 3182, . . . , 318p) to the computer system (102) which execute in user mode on a trusted secure desktop (904). The trusted secure desktop is configured to run simultaneously with an unsecure desktop (902). The methods also involve performing a security service operation to protect the first end user application against malware. The security service operations include a keylogger prevention service operation, a code injection prevention service operation, a screen scraper protection service operation, a process termination prevention service operation, or a Domain Name System service operation.