Cases for electronic devices, such as an iPad, are disclosed. The cases include an integrated cleaning component configured to wipe one or more surfaces of an electronic device. In some embodiments, the integrated cleaning component is configured to automatically wipe the surface(s) of the electronic device as it is inserted into or removed from the case. The integrated cleaning component of some embodiments include strips of material configured to engage the surface of the electronic device as it is inserted and/or removed from the case and to wipe or scrub away foreign material. The cleaning component can include various different materials to target primary removal of a particular foreign material (e.g., fingerprints, dirt, dust, oils, etc.). Other embodiments provide integrated storage of the integrated cleaning component, which can easily be removed by a user to wipe the surface(s) of the electronic device.