Vibration isolation devices and associated systems and methods are disclosed herein. In one embodiment, for example, an unmanned aircraft can include a fuselage having a first fuselage section and a second fuselage section adjacent to and at least approximately longitudinally aligned with the first fuselage section. The aircraft can also include at least one vibration isolation device coupling the first fuselage section to the second fuselage section. The vibration isolation device is translationally stiffer along a longitudinal axis than it is along a lateral and a vertical axis, and rotationally stiffer about a pitch and a yaw axis than it is about a roll axis.