Invention Grant
US08226982B2 Inhalable powders comprising protein, phenylalanine, and other protein stabilizers
有权
包含蛋白质,苯丙氨酸和其他蛋白质稳定剂的可吸入粉末
- Patent Title: Inhalable powders comprising protein, phenylalanine, and other protein stabilizers
- Patent Title (中): 包含蛋白质,苯丙氨酸和其他蛋白质稳定剂的可吸入粉末
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Application No.: US11766940Application Date: 2007-06-22
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Publication No.: US08226982B2Publication Date: 2012-07-24
- Inventor: Torsten Schultz-Fademrecht , Patrick Garidel , Beate Fischer , Karoline Bechtold-Peters
- Applicant: Torsten Schultz-Fademrecht , Patrick Garidel , Beate Fischer , Karoline Bechtold-Peters
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
- Current Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Anthony P. Bottino
- Priority: DE102006030164 20060629
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/14 ; A61K31/195 ; A61K38/00 ; A61K38/18 ; A61K38/23 ; A61K38/28

Abstract:
The invention therefore relates to protein-containing powders, wherein the proportion of phenylalanine is at least 30% (w/w), or at least 40% (w/w). It has been shown that phenylalanine-containing powders, particularly after spray drying, are very suitable in terms of their aerodynamic characteristics and protein stabilization for preparing powders or protein compositions with improved aerodynamic properties. The main component is phenylalanine and the optional further component is an excipient which has good water-solubility compared with phenylalanine, preferably a sugar or a polyol.
Public/Granted literature
- US20080089849A1 POWDERS FOR INHALATION Public/Granted day:2008-04-17
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