Invention Grant
- Patent Title: Method for testing or screening protein synthesis inhibitors
- Patent Title (中): 测试或筛选蛋白质合成抑制剂的方法
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Application No.: US12663161Application Date: 2008-06-04
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Publication No.: US08227203B2Publication Date: 2012-07-24
- Inventor: Gideon Dreyfuss , Mumtaz Kasim
- Applicant: Gideon Dreyfuss , Mumtaz Kasim
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Pearl Cohen Zedek Latzer, LLP
- Agent Mark S. Cohen
- International Application: PCT/US2008/006972 WO 20080604
- International Announcement: WO2008/150515 WO 20081211
- Main IPC: G01N31/00
- IPC: G01N31/00 ; G01N33/53

Abstract:
This invention provides methods for screening an inhibitor of protein synthesis by measuring the level of relocalization of an SMN complex component from the cytoplasm to the nucleus. Additionally, the invention provides a kit and a system for screening protein synthesis inhibitors in a cell.
Public/Granted literature
- US20100273179A1 METHOD FOR TESTING OR SCREENING PROTEIN SYNTHESIS INHIBITORS Public/Granted day:2010-10-28
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