Invention Grant
- Patent Title: Diketopiperazine microparticles with defined isomer contents
- Patent Title (中): 具有确定的异构体含量的二酮哌嗪微粒
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Application No.: US12813839Application Date: 2010-06-11
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Publication No.: US08227409B2Publication Date: 2012-07-24
- Inventor: Kelly S. Kraft , Karla Somerville
- Applicant: Kelly S. Kraft , Karla Somerville
- Applicant Address: US CA Valencia
- Assignee: MannKind Corporation
- Current Assignee: MannKind Corporation
- Current Assignee Address: US CA Valencia
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Brent A. Johnson
- Main IPC: A61K47/22
- IPC: A61K47/22 ; A61K38/02 ; A61K38/22 ; A61K38/28 ; A61K38/29 ; A61K38/26 ; A61K38/23 ; C07D241/08 ; A61P3/10
Abstract:
Disclosed herein are fumaryl diketopiperazine (FDKP) compositions and microparticles having a specific trans isomer content of about 45% to about 65%. The FDKP microparticles can comprise a drug such as an endocrine hormone, including, peptide, including, insulin, glucagon, parathyroid hormones and the like and can be used to make a powder formulation for pulmonary delivery of the drug.
Public/Granted literature
- US20100317574A1 Diketopiperazine Microparticles with Defined Isomer Contents Public/Granted day:2010-12-16
Information query
