Invention Grant
- Patent Title: Prostaglandin transporter inhibitors
- Patent Title (中): 前列腺素转运蛋白抑制剂
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Application No.: US12227267Application Date: 2007-05-15
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Publication No.: US08227466B2Publication Date: 2012-07-24
- Inventor: Victor L. Schuster , Yuling Chi , Young-Tae Chang , Jaeki Min
- Applicant: Victor L. Schuster , Yuling Chi , Young-Tae Chang , Jaeki Min
- Applicant Address: US NY Bronx
- Assignee: Albert Einstein College of Medicine of Yeshiva University
- Current Assignee: Albert Einstein College of Medicine of Yeshiva University
- Current Assignee Address: US NY Bronx
- Agency: Amster, Rothstein & Ebenstein
- International Application: PCT/US2007/011693 WO 20070515
- International Announcement: WO2007/136638 WO 20071129
- Main IPC: A61K31/53
- IPC: A61K31/53 ; C07D251/54
Abstract:
Provided are methods of inhibiting prostaglandin transporter (PGT) activity in mammals. Also provided are methods of determining whether a test compound is an inhibitor of a prostaglandin transporter. Additionally provided are compounds that inhibit prostaglandin transporter activity, and pharmaceutical compositions of those compounds. Methods of inhibiting COX-2 in a mammal are also provided. Additionally, methods of treating pain or inflammation in a mammal are provided.
Public/Granted literature
- US20090233933A1 Prostaglandin Transporter Inhibitors Public/Granted day:2009-09-17
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