Invention Grant
- Patent Title: Pyridyl derivatives as CFTR modulators
- Patent Title (中): 吡啶衍生物作为CFTR调节剂
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Application No.: US12410725Application Date: 2009-03-25
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Publication No.: US08227615B2Publication Date: 2012-07-24
- Inventor: Sara Hadida-Ruah , Mark Miller , Jinglan Zhou , Brian Bear , Peter Grootenhuis
- Applicant: Sara Hadida-Ruah , Mark Miller , Jinglan Zhou , Brian Bear , Peter Grootenhuis
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceutical Incorporated
- Current Assignee: Vertex Pharmaceutical Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael J. DiVerdi
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D405/00
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20090246137A1 PYRIDYL DERIVATIVES AS CFTR MODULATORS Public/Granted day:2009-10-01
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