Invention Grant
- Patent Title: Pharmaceutical compounds
- Patent Title (中): 药物化合物
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Application No.: US12645415Application Date: 2009-12-22
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Publication No.: US08227620B2Publication Date: 2012-07-24
- Inventor: Paolo Lazzari , Stefania Ruiu , Gerard Aime Pinna , Gabriele Murineddu
- Applicant: Paolo Lazzari , Stefania Ruiu , Gerard Aime Pinna , Gabriele Murineddu
- Applicant Address: IT Cagliari
- Assignee: Neuroscienze Pharmaness S.C. A.R.L.
- Current Assignee: Neuroscienze Pharmaness S.C. A.R.L.
- Current Assignee Address: IT Cagliari
- Agency: Womble Carlyle Sandridge & Rice, LLP
- Priority: ITMI2004A1032 20040524
- Main IPC: A61K31/4155
- IPC: A61K31/4155 ; A61K31/454

Abstract:
Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: R is a group selected from C1-C10 alkyl; aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; A is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R″ wherein v is equal to 1 or 2; R″ is as defined in the present application; a ketone group of formula —C(O)—Z′, wherein Z′ is as defined in the present application; a substituent having an hydroxyl function of formula —CH(OH)—Z′, being as defined in the present application; an amide substituent of formula —C(O)—NH-T′, T′ being as defined in the present application; B is a group as defined in the present application; D is an heteroaryl optionally substituted.
Public/Granted literature
- US20100105896A1 PHARMACEUTICAL COMPOUNDS Public/Granted day:2010-04-29
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