Invention Grant
US08232272B2 Benzimidazoledihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, and pharmaceutical compositions comprising same
失效
作为果糖-1,6-二磷酸酶抑制剂的苯并咪唑并二氢噻二酮衍生物和包含其的药物组合物
- Patent Title: Benzimidazoledihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, and pharmaceutical compositions comprising same
- Patent Title (中): 作为果糖-1,6-二磷酸酶抑制剂的苯并咪唑并二氢噻二酮衍生物和包含其的药物组合物
-
Application No.: US12742375Application Date: 2008-10-13
-
Publication No.: US08232272B2Publication Date: 2012-07-31
- Inventor: Gerard Botton , Caroline Leriche , Annick Arbellot de Vacqueur , Annick Audet , Johannes Gleitz
- Applicant: Gerard Botton , Caroline Leriche , Annick Arbellot de Vacqueur , Annick Audet , Johannes Gleitz
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
- Current Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: EP07291349 20071112
- International Application: PCT/EP2008/008631 WO 20081013
- International Announcement: WO2009/062576 WO 20090522
- Main IPC: C07D417/04
- IPC: C07D417/04 ; C07D417/14 ; A61K31/54

Abstract:
The present invention relates to novel benzimidazole-dihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, to processes for the preparation thereof and to the use thereof in therapy, especially for the treatment of diabetes.
Public/Granted literature
Information query