Invention Grant
US08232279B2 Pyrazolopyrimidine derivatives having biological activity on serotonin receptor 5-HT2c
有权
对5-羟色胺受体5-HT2c具有生物活性的吡唑并嘧啶衍生物
- Patent Title: Pyrazolopyrimidine derivatives having biological activity on serotonin receptor 5-HT2c
- Patent Title (中): 对5-羟色胺受体5-HT2c具有生物活性的吡唑并嘧啶衍生物
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Application No.: US12575235Application Date: 2009-10-07
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Publication No.: US08232279B2Publication Date: 2012-07-31
- Inventor: Ae Nim Pae , Hyunah Choo , Yong Seo Cho , Ahmed Asif , Woo-Kyu Park
- Applicant: Ae Nim Pae , Hyunah Choo , Yong Seo Cho , Ahmed Asif , Woo-Kyu Park
- Applicant Address: KR Seoul
- Assignee: Korea Institute of Science and Technology
- Current Assignee: Korea Institute of Science and Technology
- Current Assignee Address: KR Seoul
- Agency: Frommer Lawrence & Haug LLP
- Agent Ronald R Santucci
- Priority: KR10-2009-0043728 20090519
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D487/00
Abstract:
The present invention relates to a novel medicinal use of pyrazolopyrimidine compounds having superior effect as serotonin 5-HT2C receptor ligand thus being useful for the prevention and treatment of central nervous system (CNS) diseases. Accordingly, the pharmaceutical composition comprising pyrazolopyrimidine compounds and their pharmaceutically acceptable salts as active ingredients are useful for the prevention and treatment of serotonin 5-HT2C-related central nervous system diseases such as obesity, depression, anxiety and withdrawal symptoms due to drug abuse.
Public/Granted literature
- US20100298563A1 PYRAZOLOPYRIMIDINE DERIVATIVES HAVING BIOLOGICAL ACTIVITY ON SEROTONIN RECEPTOR 5-HT2c Public/Granted day:2010-11-25
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