Invention Grant
US08235910B2 Systems and methods for model-based estimation of cardiac ejection fraction, cardiac contractility, and ventricular end-diastolic volume
有权
用于基于模型估计心脏射血分数，心脏收缩力和心室舒张末期容量的系统和方法
- Patent Title: Systems and methods for model-based estimation of cardiac ejection fraction, cardiac contractility, and ventricular end-diastolic volume
- Patent Title (中): 用于基于模型估计心脏射血分数，心脏收缩力和心室舒张末期容量的系统和方法
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Application No.: US12121878Application Date: 2008-05-16
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Publication No.: US08235910B2Publication Date: 2012-08-07
- Inventor: Tushar A. Parlikar , George C. Verghese , Thomas Heldt , Ramakrisna Mukkamala
- Applicant: Tushar A. Parlikar , George C. Verghese , Thomas Heldt , Ramakrisna Mukkamala
- Agency: Ropes & Gray LLP
- Main IPC: A61B5/02
- IPC: A61B5/02
Abstract:
The methods and systems for estimating cardiac ejection fraction, cardiac contractility, and ventricular end-diastolic volume on a beat-by-beat basis include observing arterial blood pressure waveforms to determine ventricular compliances for a pressure-volume loop in the ventricle. Uncalibrated or calibrated cardiac ejection fraction may be calculated from estimates of stroke volume and the ventricular compliances. Cardiac contractility may be calculated from estimates of a ventricular compliance. Uncalibrated or calibrated ventricular end-diastolic volume may also be calculated from estimates of stroke volume and the ventricular compliances. A set of calibration parameters for calibrating cardiac ejection fraction or ventricular end-diastolic volume may be estimated in a least-squares manner.
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