Invention Grant
US08236328B2 Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers
有权
与聚合物混合的无定形药物的分散体的药物组合物
- Patent Title: Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers
- Patent Title (中): 与聚合物混合的无定形药物的分散体的药物组合物
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Application No.: US12217700Application Date: 2008-07-08
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Publication No.: US08236328B2Publication Date: 2012-08-07
- Inventor: Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- Applicant: Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- Applicant Address: US OR Bend
- Assignee: Bend Research, Inc.
- Current Assignee: Bend Research, Inc.
- Current Assignee Address: US OR Bend
- Agency: Chernoff, Vilhauer, McClung & Stenzel
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/14
Abstract:
A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.
Public/Granted literature
- US20090011024A1 Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers Public/Granted day:2009-01-08
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