Invention Grant
US08236513B2 Determining and reducing immunoresistance to botulinum toxin therapy using botulinum toxin A peptides
有权
使用肉毒杆菌毒素A肽确定和降低对肉毒杆菌毒素治疗的免疫耐受性
- Patent Title: Determining and reducing immunoresistance to botulinum toxin therapy using botulinum toxin A peptides
- Patent Title (中): 使用肉毒杆菌毒素A肽确定和降低对肉毒杆菌毒素治疗的免疫耐受性
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Application No.: US12192955Application Date: 2008-08-15
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Publication No.: US08236513B2Publication Date: 2012-08-07
- Inventor: M. Zouhair Atassi
- Applicant: M. Zouhair Atassi
- Applicant Address: US TX Houston
- Assignee: Baylor College of Medicine
- Current Assignee: Baylor College of Medicine
- Current Assignee Address: US TX Houston
- Agent Kenton Abel; Debra Condino
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The present invention provides BoNT/A peptide compositions, tolerogizing compositions, BoNT/A immune response inducing compositions and antibody compositions, as well as methods of determining immunoresistance to botulinum toxin therapy in an individual, methods of preventing or reducing immunoresistance to botulinum toxin therapy in an individual, methods of vaccinating an individual against botulinum toxin, methods of preparing anti-BoNT/A antibodies, methods of treating botulinum toxicity in an individual and methods of reducing anti-botulinum toxin antibodies in an individual.
Public/Granted literature
- US20090004680A1 DETERMINING AND REDUCING IMMUNORESISTANCE TO BOTULINUM TOXIN THERAPY USING BOTULINUM TOXIN A PEPTIDES Public/Granted day:2009-01-01
Information query
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