Invention Grant
- Patent Title: Benzothiadiazepine compounds, a process for their preparation and pharmaceutical compositions containing them
- Patent Title (中): 苯并噻二嗪类化合物,其制备方法和含有它们的药物组合物
-
Application No.: US12661598Application Date: 2010-03-19
-
Publication No.: US08236790B2Publication Date: 2012-08-07
- Inventor: Alexis Cordi , Patrice Desos , Pierre Lestage , Laurence Danober
- Applicant: Alexis Cordi , Patrice Desos , Pierre Lestage , Laurence Danober
- Applicant Address: FR Suresnes Cedex
- Assignee: Les Laboratories Servier
- Current Assignee: Les Laboratories Servier
- Current Assignee Address: FR Suresnes Cedex
- Agency: Hueschen and Sage
- Priority: FR0901300 20090320
- Main IPC: C07D285/36
- IPC: C07D285/36 ; A61K31/554

Abstract:
Compounds of formula (I): wherein: R1 and R2, which may be the same or different, each represent a hydrogen or halogen atom or an alkyl, alkoxy, alkylthio, acyl, alkoxycarbonyl, carboxy, hydroxy, hydroxyalkyl, cyano, nitro, amino, substituted or unsubstituted aminocarbonyl, aminosulphonyl, alkylsulphonylaminoalkyl, N-hydroxy-carboximidamide or benzyloxy group, R3 represents a hydrogen atom or an alkyl, cycloalkyl or cycloalkylalkyl group, R4 represents a hydrogen atom or a substituted or unsubstituted alkyl group Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator and/or an NMDA receptor antagonist.
Public/Granted literature
Information query