Invention Grant
US08236803B2 Aza-bicycloalkyl ethers and their use as alpha7-nAChR agonists
有权
氮杂双环烷基醚及其作为α7-nAChR激动剂的用途
- Patent Title: Aza-bicycloalkyl ethers and their use as alpha7-nAChR agonists
- Patent Title (中): 氮杂双环烷基醚及其作为α7-nAChR激动剂的用途
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Application No.: US12262896Application Date: 2008-10-31
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Publication No.: US08236803B2Publication Date: 2012-08-07
- Inventor: Dominik Feuerbach , Konstanze Hurth , Timothy John Ritchie
- Applicant: Dominik Feuerbach , Konstanze Hurth , Timothy John Ritchie
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Strain & Strain PLLC
- Agent Paul D. Strain
- Priority: GB220581.3 20020904
- Main IPC: A61K31/501
- IPC: A61K31/501 ; C07D401/12 ; A61P25/18 ; A61P25/16 ; A61P25/28 ; A61P25/08 ; A61P9/10
Abstract:
The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, wherein X is CH2 or a single bond; Y is a group of formula and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
Public/Granted literature
- US20090054446A1 AZA-BICYCLOALKYL ETHERS AND THEIR USE AS ALPHA7-NACHR AGONISTS Public/Granted day:2009-02-26
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