Invention Grant
- Patent Title: Compounds
- Patent Title (中): 化合物
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Application No.: US12478587Application Date: 2009-06-04
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Publication No.: US08236827B2Publication Date: 2012-08-07
- Inventor: Gerard Andrew Potter , Philip Huxley , Kenneth James Beresford
- Applicant: Gerard Andrew Potter , Philip Huxley , Kenneth James Beresford
- Applicant Address: GB Leicester
- Assignee: Spear Therapeutics Limited
- Current Assignee: Spear Therapeutics Limited
- Current Assignee Address: GB Leicester
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Jennifer L. Loebach; Yongjun Zhang
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/44 ; C07D405/00

Abstract:
A compound for use in the treatment of proliferative disorders, such as cancer, having the following formula: wherein: R1, R2 and R3 are independently H or lower alkyl; R4, R5, R6, R7 and R8 are independently H, halo, lower alkyl or —O-lower alkyl, provided that at least one is —O-lower alkyl; or at least one pair of R4 to R8, the members of which pair are adjacent to one another on the ring, are conjoined to form —O—(CR14R15)n—O—, where n is 1 or 2 and R14 and R15 are independently H or lower alkyl, and the remainder of R4 to R8 are independently H, halo, lower alkyl or —O-lower alkyl; and R9, R10, R11, R12 and R13 are independently H, halo, lower alkyl or —O— lower alkyl, provided that at least one is —O-lower alkyl; or at least one pair of R9 to R13, the members of which pair are adjacent to one another on the ring, are conjoined to form —O—(CR16R17)m—O—, where m is 1 or 2 and R16 and R17 are independently H or lower alkyl, and the remainder of R9 to R13 are independently H, halo, lower alkyl or —O-lower alkyl.
Public/Granted literature
- US20100168180A1 Novel Compounds Public/Granted day:2010-07-01
Information query
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