Invention Grant
US08236834B2 Crystalline forms of thiazolidinedione compound and its manufacturing method
失效
噻唑烷二酮化合物的结晶形式及其制备方法
- Patent Title: Crystalline forms of thiazolidinedione compound and its manufacturing method
- Patent Title (中): 噻唑烷二酮化合物的结晶形式及其制备方法
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Application No.: US12311610Application Date: 2008-02-08
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Publication No.: US08236834B2Publication Date: 2012-08-07
- Inventor: Hisaki Kajino , Yutaka Ikeuchi , Eiji Numagami
- Applicant: Hisaki Kajino , Yutaka Ikeuchi , Eiji Numagami
- Applicant Address: JP Tokyo
- Assignee: Daiichi Sankyo Company, Limited
- Current Assignee: Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Tokyo
- Agency: Holtz, Holtz, Goodman & Chick, P.C.
- International Application: PCT/JP2008/052594 WO 20080208
- International Announcement: WO2008/099944 WO 20080821
- Main IPC: A61K31/427
- IPC: A61K31/427 ; C07D277/34

Abstract:
It is an object of the present invention to provide the crystalline form of a thiazolidinedione compound, which is effective as a pharmaceutical ingredient for manufacturing a peroxisome proliferator-activated receptor (PPAR) activator and an anticancer pharmaceutical composition. The present invention relates to a crystalline form of a hydrate of 5-(4-{[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1-H-benzimidazol-2-yl]methoxy}benzyl)-1,3-thiazolidine-2,4-dione dihydrochloride represented by the following formula (I). [Formula 1]
Public/Granted literature
- US20110213158A9 Crystalline forms of thiazolidinedione compound and its manufacturing method Public/Granted day:2011-09-01
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