A method of pattern matching applicable to a transmission flow which is divided into multiple segments is provided, including: determining whether there is flow status information corresponding to a current pattern for a transmission flow to which a current segment belongs; creating the flow status information corresponding to the current pattern for the transmission flow if there is no flow status information corresponding to the current pattern for the transmission flow to which the current segment belongs; performing pattern matching for the current segment by taking the flow status information as assistant information of the pattern matching. An apparatus of pattern matching applicable to a transmission flow which is divided into multiple segments is also provided, including a flow status information configuration module and a pattern matching processing module. The solution of the present invention can avoid the defects caused by flow-reassembly.