Various aspects of this disclosure are directed to determining an orientation of a mobile computing device. The mobile computing device may include a first microphone-speaker system and a second microphone-speaker system that can each provide microphone and speaker capabilities. The first microphone-speaker system may be enabled to operate as a speaker device. The enabling of the first microphone-speaker system may include allowing the first microphone-speaker system to provide audio output and disallowing the mobile computing device to process audio input received from the first microphone-speaker system. The second microphone-speaker system may be enabled to operate as a microphone. Enabling the second microphone-speaker system may include allowing the mobile computing device to process audio input received from the second microphone-speaker system and disallowing the second microphone-speaker system to provide audio output. Enabling of the first and second microphone-speaker systems may be responsive to and based on the determined orientation.