A method, circuit arrangement, and design structure utilize a lock prediction data structure to control ownership of a cache line in a shared memory computing system. In a first node among the plurality of nodes, lock prediction data in a hardware-based lock prediction data structure for a cache line associated with a first memory request is updated in response to that first memory request, wherein at least a portion of the lock prediction data is predictive of whether the cache line is associated with a release operation. The lock prediction data is then accessed in response to a second memory request associated with the cache line and issued by a second node and a determination is made as to whether to transfer ownership of the cache line from the first node to the second node based at least in part on the accessed lock prediction data.