A skin integrated device for implantation with an improved device-skin interface for the ingrowths of skin cells and tissues throughout the pores, having a solid frame, which may also be permeable.The characteristics of pore size, porosity and size of the compressed and sintered particles constitute a long-term skin integrated device for transfer of vital and therapeutic substances, and necessary forces and moments from the outer delivery and prosthetics devices to the human body. The ingrowth of the skin along with the intermittent layer of fine silver provides a barrier for infection.