Invention Grant
US08257696B2 Indefinite culture of human adult glia without immortalization and therapeutic uses thereof
失效
人类成年胶质细胞的无限期培养，无永生化及其治疗用途
- Patent Title: Indefinite culture of human adult glia without immortalization and therapeutic uses thereof
- Patent Title (中): 人类成年胶质细胞的无限期培养，无永生化及其治疗用途
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Application No.: US11719039Application Date: 2005-11-21
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Publication No.: US08257696B2Publication Date: 2012-09-04
- Inventor: Dennis A. Steindler , Noah M. Walton
- Applicant: Dennis A. Steindler , Noah M. Walton
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Inc.
- Current Assignee: University of Florida Research Foundation, Inc.
- Current Assignee Address: US FL Gainesville
- Agency: Thomas, Kayden, Horstemeyer & Risley, LLP
- International Application: PCT/US2005/041978 WO 20051121
- International Announcement: WO2006/055841 WO 20060526
- Main IPC: A61K35/30
- IPC: A61K35/30 ; C12N5/079 ; C12N5/0797
Abstract:
Cell culture conditions for the isolation, maintenance, and indefinite expansion of human glia are established favoring the growth of neural precursor cells. Cultured cells proliferate indefinitely, express catalytic telomerase, and retain a non-immortalized phenotype. Compositions allow for the indefinite expansion of non-immortalized neural tissue for bioassay applications and restorative neuroscience.
Public/Granted literature
- US20100150875A1 INDEFINITE CULTURE OF HUMAN ADULT GLIA WITHOUT IMMORTALIZATION AND THERAPEUTIC USES THEREOF Public/Granted day:2010-06-17
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