Invention Grant
- Patent Title: Anti-sclerostin antibodies
- Patent Title (中): 抗硬化蛋白抗体
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Application No.: US13165126Application Date: 2011-06-21
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Publication No.: US08257704B2Publication Date: 2012-09-04
- Inventor: Andrew Ihor Korytko , David Matthew Marquis , Eric Michael Smith , Barbara Anne Swanson
- Applicant: Andrew Ihor Korytko , David Matthew Marquis , Eric Michael Smith , Barbara Anne Swanson
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Gregory A. Cox; Andrea M. Castetter
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/00 ; C07K16/18 ; C07K16/22 ; C07K16/24
Abstract:
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
Public/Granted literature
- US20110250205A1 ANTI-SCLEROSTIN ANTIBODIES Public/Granted day:2011-10-13
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