Invention Grant
US08257745B2 Use of synthetic inorganic nanoparticles as carriers for ophthalmic and otic drugs
有权
使用合成无机纳米粒子作为眼科和耳用药物的载体
- Patent Title: Use of synthetic inorganic nanoparticles as carriers for ophthalmic and otic drugs
- Patent Title (中): 使用合成无机纳米粒子作为眼科和耳用药物的载体
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Application No.: US13186108Application Date: 2011-07-19
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Publication No.: US08257745B2Publication Date: 2012-09-04
- Inventor: Howard Allen Ketelson , David L. Meadows
- Applicant: Howard Allen Ketelson , David L. Meadows
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Gregg C. Brown; Michael D. Rein
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K38/18 ; A61P27/06 ; A61P25/00 ; A61P31/00 ; A61P29/00 ; A61P37/08 ; A61P37/02 ; B82Y5/00
Abstract:
The use of nanoparticles of inorganic materials (e.g., synthetic smectite clays) in ophthalmic and otic pharmaceutical compositions is described. The nanoparticles are utilized as biologically inert carriers or depots for ophthalmic and otic drugs. The nanoparticles may also be utilized to modify the rheological properties of the compositions, so as to enhance the viscosity or flow characteristics of the compositions and/or increase the retention time of the compositions in the eye or ear.
Public/Granted literature
- US20110274760A1 USE OF SYNTHETIC INORGANIC NANOPARTICLES AS CARRIERS FOR OPHTHALMIC AND OTIC DRUGS Public/Granted day:2011-11-10
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