Invention Grant
- Patent Title: Bisulfite conversion of DNA
- Patent Title (中): 亚硫酸氢盐转化DNA
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Application No.: US13159323Application Date: 2011-06-13
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Publication No.: US08257950B2Publication Date: 2012-09-04
- Inventor: Kurt Berlin , Matthias Ballhause , Karen Cardon
- Applicant: Kurt Berlin , Matthias Ballhause , Karen Cardon
- Applicant Address: DE Berlin
- Assignee: Epigenomics AG
- Current Assignee: Epigenomics AG
- Current Assignee Address: DE Berlin
- Agency: DLA Piper LLP (US)
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12Q1/68
Abstract:
The present invention provides an improved method for the bisulfite conversion of DNA, and facilitates the analysis of cytosine methylation of genomic DNA. Novel combinations of denaturing solvents, new reaction conditions and new purification methods provide surprisingly efficacious methods for bisulfite conversion of DNA relative to prior art methods. The converted DNA may subsequently be analyzed by many different methods.
Public/Granted literature
- US20110250601A1 Bisulfite Conversion of DNA Public/Granted day:2011-10-13
Information query
