Invention Grant
- Patent Title: Immunostimulatory nucleic acid molecules
- Patent Title (中): 免疫刺激核酸分子
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Application No.: US11598207Application Date: 2006-11-10
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Publication No.: US08258106B2Publication Date: 2012-09-04
- Inventor: Arthur M. Krieg , Joel N. Kline , Dennis Klinman , Alfred D. Steinberg
- Applicant: Arthur M. Krieg , Joel N. Kline , Dennis Klinman , Alfred D. Steinberg
- Applicant Address: US IA Iowa City US NY New York US DC Washington
- Assignee: University of Iowa Research Foundation,Coley Pharmaceutical Group, Inc.,The United States of America, as represented by the Department of Health and Human Services
- Current Assignee: University of Iowa Research Foundation,Coley Pharmaceutical Group, Inc.,The United States of America, as represented by the Department of Health and Human Services
- Current Assignee Address: US IA Iowa City US NY New York US DC Washington
- Agency: Wolf, Greenfield & Sacks, P.C.
- Agent Gregg C. Benson
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/38 ; A61K39/145 ; A61K38/00 ; A61K31/70 ; A01N37/18 ; A01N43/04
Abstract:
Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
Public/Granted literature
- US20080031936A1 Immunostimulatory nucleic acid molecules Public/Granted day:2008-02-07
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