Invention Grant
- Patent Title: Small-molecule agonists for type-2 orexin receptor
- Patent Title (中): 2型食欲素受体的小分子激动剂
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Application No.: US12478753Application Date: 2009-06-04
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Publication No.: US08258163B2Publication Date: 2012-09-04
- Inventor: Masashi Yanagisawa
- Applicant: Masashi Yanagisawa
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Richard Aron Osman
- Main IPC: A61K31/4168
- IPC: A61K31/4168
Abstract:
Methods and compositions for agonizing a type-2 orexin receptor (OX2R) in a cell determined to be in need thereof, including the general method of (a) administering to a subject a cyclic guanidinyl OX2R agonist and (b) detecting a resultant enhanced wakefulness or increased resistance to diet-induced accumulation of body fat, or abbreviated recovery from general anesthesia or jet lag.
Public/Granted literature
- US20100150840A1 Small-molecule agonists for type-2 orexin receptor Public/Granted day:2010-06-17
Information query
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