Invention Grant
- Patent Title: pH-sensitive fluorescent probe
- Patent Title (中): pH敏感荧光探针
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Application No.: US12447723Application Date: 2007-11-15
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Publication No.: US08258171B2Publication Date: 2012-09-04
- Inventor: Tetsuo Nagano , Yasuteru Urano , Daisuke Asanuma
- Applicant: Tetsuo Nagano , Yasuteru Urano , Daisuke Asanuma
- Applicant Address: JP Tokyo
- Assignee: The University of Tokyo
- Current Assignee: The University of Tokyo
- Current Assignee Address: JP Tokyo
- Agency: Greenblum and Bernstein, P.L.C.
- Priority: JP2006-308538 20061115
- International Application: PCT/JP2007/072159 WO 20071115
- International Announcement: WO2008/059910 WO 20080522
- Main IPC: A61K31/40
- IPC: A61K31/40 ; C07D209/56

Abstract:
A compound represented by the following general formula (I): wherein R1 represents an amino group which may be substituted with one or two alkyl groups; R2, R3, R4 and R5 independently represent an alkyl group; and R6 and R7 independently represent a monocarboxyalkyl group, a salt thereof, or an ester thereof, which is useful as a pH-sensitive fluorescent probe which emits intense fluorescence in an acidic region.
Public/Granted literature
- US20100068733A1 pH-Sensitive Fluorescent Probe Public/Granted day:2010-03-18
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