Invention Grant
US08258262B2 N-terminally chemically modified protein compositions and methods
失效
N-末端化学修饰的蛋白质组合物和方法
- Patent Title: N-terminally chemically modified protein compositions and methods
- Patent Title (中): N-末端化学修饰的蛋白质组合物和方法
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Application No.: US12639398Application Date: 2009-12-16
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Publication No.: US08258262B2Publication Date: 2012-09-04
- Inventor: Olaf B. Kinstler , Nancy Elise Gabriel , Christine E. Farrar , Randolph B. DePrince
- Applicant: Olaf B. Kinstler , Nancy Elise Gabriel , Christine E. Farrar , Randolph B. DePrince
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K14/00 ; C07K17/00 ; A61K38/16
Abstract:
Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
Public/Granted literature
- US20100310510A1 N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS Public/Granted day:2010-12-09
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