Invention Grant
- Patent Title: Modulation of diacylglycerol acyltransferase 2 expression
- Patent Title (中): 二酰基甘油酰基转移酶2表达的调控
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Application No.: US12748281Application Date: 2010-03-26
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Publication No.: US08258289B2Publication Date: 2012-09-04
- Inventor: Sanjay Bhanot , Kenneth W. Dobie , Xing-Xian Yu , Brett P. Monia
- Applicant: Sanjay Bhanot , Kenneth W. Dobie , Xing-Xian Yu , Brett P. Monia
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc
- Current Assignee: Isis Pharmaceuticals, Inc
- Current Assignee Address: US CA Carlsbad
- Agency: Jones Day
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
Compounds, compositions and methods are provided for modulating the expression of diacylglycerol acyltransferase 2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding diacylglycerol acyltransferase 2. Methods of using these compounds for modulation of diacylglycerol acyltransferase 2 expression and for diagnosis and treatment of diseases and conditions associated with expression of diacylglycerol acyltransferase 2 are provided.
Public/Granted literature
- US20100311810A1 MODULATION OF DIACYLGLYCEROL ACYLTRANSFERASE 2 EXPRESSION Public/Granted day:2010-12-09
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