Invention Grant
US08258295B2 Triazine derivatives, compositions containing such derivatives, and methods of treatment of cancer and autoimmune diseases using such derivatives
有权
三嗪衍生物,含有这些衍生物的组合物,以及使用这些衍生物治疗癌症和自身免疫性疾病的方法
- Patent Title: Triazine derivatives, compositions containing such derivatives, and methods of treatment of cancer and autoimmune diseases using such derivatives
- Patent Title (中): 三嗪衍生物,含有这些衍生物的组合物,以及使用这些衍生物治疗癌症和自身免疫性疾病的方法
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Application No.: US12598273Application Date: 2008-04-25
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Publication No.: US08258295B2Publication Date: 2012-09-04
- Inventor: Boulos Zacharie , Christopher Penney , Lyne Gagnon , Brigitte Grouix , Lilianne Geerts , Shaun D. Abbott
- Applicant: Boulos Zacharie , Christopher Penney , Lyne Gagnon , Brigitte Grouix , Lilianne Geerts , Shaun D. Abbott
- Applicant Address: CA Laval
- Assignee: Prometic Biosciences Inc.
- Current Assignee: Prometic Biosciences Inc.
- Current Assignee Address: CA Laval
- Agent France LeClaire
- International Application: PCT/CA2008/000796 WO 20080425
- International Announcement: WO2008/131547 WO 20081106
- Main IPC: C07D251/70
- IPC: C07D251/70 ; A61K31/53 ; A61P35/00 ; A61P37/00 ; A61P25/28 ; A61P19/02 ; A61P17/06

Abstract:
We describe compounds of the following general formula (I): wherein X is fluorine or chlorine; Y is oxygen, sulfur, or an amino group; R is an amino, hydroxyl, sulfonamide, or carboxamide group or an N-monomethyl or N-dimethyl analog thereof; m is an integer from 2 to 6, and n is an integer from 0 to 2. The compounds may be used for treating certain cancers and autoimmune diseases.
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