Invention Grant
- Patent Title: Crystalline antifungal compounds
- Patent Title (中): 结晶抗真菌化合物
-
Application No.: US12970297Application Date: 2010-12-16
-
Publication No.: US08258296B2Publication Date: 2012-09-04
- Inventor: Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- Applicant: Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- Applicant Address: ES Palau-Solita I Plegamans
- Assignee: Palau Pharma, S.A.
- Current Assignee: Palau Pharma, S.A.
- Current Assignee Address: ES Palau-Solita I Plegamans
- Agency: The Nath Law Group
- Agent Joshua B. Goldberg; Sheldon M. McGee
- Priority: EP06380225 20060807; EP07380186 20070626
- Main IPC: A61K31/517
- IPC: A61K31/517

Abstract:
The present subject matter relates to novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one represented by Formula II: , pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.
Public/Granted literature
- US20110092702A1 CRYSTALLINE ANTIFUNGAL COMPOUNDS Public/Granted day:2011-04-21
Information query
IPC分类: