Invention Grant
US08258305B2 Dopamine transporter inhibitors for use in treatment of movement disorders and other CNS indications
失效
用于治疗运动障碍和其他CNS适应症的多巴胺转运蛋白抑制剂
- Patent Title: Dopamine transporter inhibitors for use in treatment of movement disorders and other CNS indications
- Patent Title (中): 用于治疗运动障碍和其他CNS适应症的多巴胺转运蛋白抑制剂
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Application No.: US11884965Application Date: 2006-02-21
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Publication No.: US08258305B2Publication Date: 2012-09-04
- Inventor: James R. Hauske
- Applicant: James R. Hauske
- Applicant Address: US MA Boston
- Assignee: Prexa Pharmaceuticals, Inc.
- Current Assignee: Prexa Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Heidi A. Erlacher; Lian Ouyang
- International Application: PCT/US2006/006338 WO 20060221
- International Announcement: WO2006/091697 WO 20060831
- Main IPC: A61P25/00
- IPC: A61P25/00 ; A61K31/445 ; C07D211/00 ; C07D401/00
Abstract:
The invention provides a class of dopamine transporter inhibitors of formula (I) (DAT inhibitors), packaged pharmaceuticals comprising such inhibitors, and their uses in treating, or manufacturing medicaments for treating disease conditions including Parkinson's disease, when assessed by one or more of Hoehn and Yahr Staging of Parkinson's Disease, Unified Parkinson Disease Rating Scale (UPDRS), and Schwab and England Activities of Daily Living Scale. Related business methods such as marketing the inhibitors to healthcare providers are also provided.
Public/Granted literature
- US20100217727A1 Dopamine Transporter Inhibitors for Use in Treatment of Movement Disorders and Other CNS Indications Public/Granted day:2010-08-26
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