Invention Grant
- Patent Title: Enhancing efficacy of vaccines administered via the respiratory tract
- Patent Title (中): 增强通过呼吸道给药疫苗的功效
-
Application No.: US12525735Application Date: 2008-03-19
-
Publication No.: US08268307B2Publication Date: 2012-09-18
- Inventor: Parker A. Small, Jr. , Bradley S. Bender
- Applicant: Parker A. Small, Jr. , Bradley S. Bender
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Inc.
- Current Assignee: University of Florida Research Foundation, Inc.
- Current Assignee Address: US FL Gainesville
- Agency: Beusse, Wolter, Sanks, Mora & Maire, P.A.
- Agent Timothy H. Van Dyke
- International Application: PCT/US2008/057428 WO 20080319
- International Announcement: WO2008/127833 WO 20081023
- Main IPC: A61K39/145
- IPC: A61K39/145 ; A61K39/395
Abstract:
Disclosed herein are vaccine compositions comprising live attenuated virus with anti-antibody to improve efficacy. Specifically exemplified herein is a composition comprising live attenuated cold adapted influenza virus and an enhancing amount of IgG anti-IgA antibody to temporarily inactivate IgA defenses. Also disclosed herein are methods of immunizing a subject to protect against influenza comprising administering compositions taught herein.
Public/Granted literature
- US20100104562A1 Enhancing Efficacy of Vaccines Administered Via the Respiratory Tract Public/Granted day:2010-04-29
Information query
