Invention Grant
US08268572B2 Methods to identify inhibitors of Runx1-mediated expression of nociceptive receptors and ion channels
有权
识别Runx1介导的伤害感受器和离子通道表达抑制剂的方法
- Patent Title: Methods to identify inhibitors of Runx1-mediated expression of nociceptive receptors and ion channels
- Patent Title (中): 识别Runx1介导的伤害感受器和离子通道表达抑制剂的方法
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Application No.: US11884800Application Date: 2006-03-03
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Publication No.: US08268572B2Publication Date: 2012-09-18
- Inventor: Qiufu Ma , Chih-Li Chen , Clifford J. Woolf , Daniel C. Broom
- Applicant: Qiufu Ma , Chih-Li Chen , Clifford J. Woolf , Daniel C. Broom
- Applicant Address: US MA Boston US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.,The General Hospital Corporation
- Current Assignee: Dana-Farber Cancer Institute, Inc.,The General Hospital Corporation
- Current Assignee Address: US MA Boston US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2006/007578 WO 20060303
- International Announcement: WO2006/096498 WO 20060914
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53 ; G01N33/567
Abstract:
Methods are provided for identifying candidate agents for use in inhibiting expression of certain receptors and ion channels in nociceptors. Also provided are methods for identifying candidates agents for use in inhibiting neurophathic and other types of pain.
Public/Granted literature
- US20090170079A1 Regulation of RUNX1 for Treatment of Pain Public/Granted day:2009-07-02
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