Invention Grant
- Patent Title: Oximyl macrocyclic derivatives
- Patent Title (中): 甲氧基大环衍生物
-
Application No.: US12327453Application Date: 2008-12-03
-
Publication No.: US08268777B2Publication Date: 2012-09-18
- Inventor: Ying Sun , Deqiang Niu , Guoyou Xu , Yat Sun Or , Zhe Wang
- Applicant: Ying Sun , Deqiang Niu , Guoyou Xu , Yat Sun Or , Zhe Wang
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore, Esq.
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
Public/Granted literature
- US20090191153A1 OXIMYL MACROCYCLIC DERIVATIVES Public/Granted day:2009-07-30
Information query
IPC分类:
