Invention Grant
US08268844B2 Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-l-phenylalanine hydrochloride, production method thereof and use thereof
有权
N-（2,6-二氯苯甲酰基）-4- [6-（甲基氨基）甲基-1-甲基-2,4-二氧代-1,4-二氢喹唑啉-3（2H） - 基] -1的异丙酯的晶体 苯丙氨酸盐酸盐，其制备方法和用途
![Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-l-phenylalanine hydrochloride, production method thereof and use thereof](/docs/US/2012-09-18/US08268844B2/abs.jpg.600x600.jpg)
- Patent Title: Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-l-phenylalanine hydrochloride, production method thereof and use thereof
- Patent Title (中): N-（2,6-二氯苯甲酰基）-4- [6-（甲基氨基）甲基-1-甲基-2,4-二氧代-1,4-二氢喹唑啉-3（2H） - 基] -1的异丙酯的晶体 苯丙氨酸盐酸盐，其制备方法和用途
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Application No.: US12885936Application Date: 2010-09-20
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Publication No.: US08268844B2Publication Date: 2012-09-18
- Inventor: Koichi Fujita , Shinichiro Takahashi , Tatsuya Okuzumi , Tatsuhiro Yamada , Kotaro Okado , Noriyasu Kataoka , Haruko Hirashima , Hideyuki Yamaguchi
- Applicant: Koichi Fujita , Shinichiro Takahashi , Tatsuya Okuzumi , Tatsuhiro Yamada , Kotaro Okado , Noriyasu Kataoka , Haruko Hirashima , Hideyuki Yamaguchi
- Applicant Address: JP Tokyo
- Assignee: Ajinomoto Co., Inc.
- Current Assignee: Ajinomoto Co., Inc.
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2005-181219 20050621
- Main IPC: A61K31/517
- IPC: A61K31/517
![Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-l-phenylalanine hydrochloride, production method thereof and use thereof](/abs-image/US/2012/09/18/US08268844B2/abs.jpg.150x150.jpg)
Abstract:
Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-dihydroquinazoline-3(2H)-yl]-L-phenylalanine hydrochloride: are useful as α4 integrin inhibitors.
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