Invention Grant
US08268847B2 Therapeutic compositions comprising a specific endothelin receptor antagonist and a PDE5 inhibitor
有权
包含特定内皮素受体拮抗剂和PDE5抑制剂的治疗组合物
- Patent Title: Therapeutic compositions comprising a specific endothelin receptor antagonist and a PDE5 inhibitor
- Patent Title (中): 包含特定内皮素受体拮抗剂和PDE5抑制剂的治疗组合物
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Application No.: US12439290Application Date: 2007-08-28
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Publication No.: US08268847B2Publication Date: 2012-09-18
- Inventor: Martine Clozel
- Applicant: Martine Clozel
- Applicant Address: CH Allschwil
- Assignee: Actelion Pharmaceuticals, Ltd.
- Current Assignee: Actelion Pharmaceuticals, Ltd.
- Current Assignee Address: CH Allschwil
- Agency: Hoxie & Associates LLC
- Priority: WOPCT/IB2006/052999 20060829; WOPCT/IB2006/053857 20061019
- International Application: PCT/IB2007/053448 WO 20070828
- International Announcement: WO2008/026156 WO 20080306
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D401/00

Abstract:
The invention relates to a product containing the compound of formula (I) below or a pharmaceutically acceptable salt of this compound, in combination with at least one compound having PDE5-inhibitory properties, or a pharmaceutically acceptable salt thereof, for therapeutic use, simultaneously, separately or over a period of time, in the treatment of a disease wherein vasoconstriction is involved.
Public/Granted literature
- US20090318459A1 Therapeutic Compositions Comprising a Specific Endothelin Receptor Antagonist and a PDE5 Inhibitor Public/Granted day:2009-12-24
Information query
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