Invention Grant
US08268847B2 Therapeutic compositions comprising a specific endothelin receptor antagonist and a PDE5 inhibitor 有权
包含特定内皮素受体拮抗剂和PDE5抑制剂的治疗组合物

  • Patent Title: Therapeutic compositions comprising a specific endothelin receptor antagonist and a PDE5 inhibitor
  • Patent Title (中): 包含特定内皮素受体拮抗剂和PDE5抑制剂的治疗组合物
  • Application No.: US12439290
    Application Date: 2007-08-28
  • Publication No.: US08268847B2
    Publication Date: 2012-09-18
  • Inventor: Martine Clozel
  • Applicant: Martine Clozel
  • Applicant Address: CH Allschwil
  • Assignee: Actelion Pharmaceuticals, Ltd.
  • Current Assignee: Actelion Pharmaceuticals, Ltd.
  • Current Assignee Address: CH Allschwil
  • Agency: Hoxie & Associates LLC
  • Priority: WOPCT/IB2006/052999 20060829; WOPCT/IB2006/053857 20061019
  • International Application: PCT/IB2007/053448 WO 20070828
  • International Announcement: WO2008/026156 WO 20080306
  • Main IPC: A01N43/54
  • IPC: A01N43/54 A61K31/505 C07D401/00
Therapeutic compositions comprising a specific endothelin receptor antagonist and a PDE5 inhibitor
Abstract:
The invention relates to a product containing the compound of formula (I) below or a pharmaceutically acceptable salt of this compound, in combination with at least one compound having PDE5-inhibitory properties, or a pharmaceutically acceptable salt thereof, for therapeutic use, simultaneously, separately or over a period of time, in the treatment of a disease wherein vasoconstriction is involved.
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