Invention Grant
- Patent Title: Cyclopropane compound
- Patent Title (中): 环丙烷化合物
-
Application No.: US13237205Application Date: 2011-09-20
-
Publication No.: US08268848B2Publication Date: 2012-09-18
- Inventor: Taro Terauchi , Ayumi Takemura , Takashi Doko , Yu Yoshida , Toshiaki Tanaka , Keiichi Sorimachi , Yoshimitsu Naoe , Carsten Beuckmann , Yuji Kazuta
- Applicant: Taro Terauchi , Ayumi Takemura , Takashi Doko , Yu Yoshida , Toshiaki Tanaka , Keiichi Sorimachi , Yoshimitsu Naoe , Carsten Beuckmann , Yuji Kazuta
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Priority: JP2010-211629 20100922
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505

Abstract:
A cyclopropane compound represented by the following formula (A) or a pharmaceutically acceptable salt thereof has orexin receptor antagonism, and therefore has a potencial of usefulness for the treatment of sleep disorder for which orexin receptor antagonism is effective, for example, insomnia: wherein Q represents —CH— or a nitrogen atom, R1a and R1b each independently represent a C1-6 alkyl group and the like, R1c represents a hydrogen atom and the like, R2a, R2b, R2c and R2d each independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group and the like, R3a, R3b and R3c each independently represent a hydrogen atom, a halogen atom and the like, and R3d represents a hydrogen atom and the like.
Public/Granted literature
- US20120095031A1 CYCLOPROPANE COMPOUND Public/Granted day:2012-04-19
Information query
IPC分类: