Invention Grant
- Patent Title: Aminotetrahydroindazoloacetic acids
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Application No.: US13324650Application Date: 2011-12-13
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Publication No.: US08268870B2Publication Date: 2012-09-18
- Inventor: Li Chen , Fariborz Firooznia , Paul Gillespie , Yun He , Tai-An Lin , Sung-Sau So , HongYing Yun
- Applicant: Li Chen , Fariborz Firooznia , Paul Gillespie , Yun He , Tai-An Lin , Sung-Sau So , HongYing Yun
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Dennis P. Tramaloni; Brian C. Remy
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D401/12

Abstract:
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, R1-R3 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
Public/Granted literature
- US20120095053A1 AMINOTETRAHYDROINDAZOLOACETIC ACIDS Public/Granted day:2012-04-19
Information query
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