Invention Grant
US08268882B2 Triptolide C-ring derivatives as anticancer agents and immune modulators
有权
雷公藤内酯C环衍生物作为抗癌剂和免疫调节剂
- Patent Title: Triptolide C-ring derivatives as anticancer agents and immune modulators
- Patent Title (中): 雷公藤内酯C环衍生物作为抗癌剂和免疫调节剂
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Application No.: US13147587Application Date: 2010-02-04
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Publication No.: US08268882B2Publication Date: 2012-09-18
- Inventor: John H. Musser
- Applicant: John H. Musser
- Applicant Address: US CA Redwood City
- Assignee: Pharmagenesis, Inc.
- Current Assignee: Pharmagenesis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: King & Spalding LLP
- Agent Peter J. Dehlinger; Susan J. Myers Fitch
- International Application: PCT/US2010/023220 WO 20100204
- International Announcement: WO2010/091193 WO 20100812
- Main IPC: A61K31/365
- IPC: A61K31/365 ; C07D493/14 ; C07D493/22
Abstract:
Disclosed are compounds based on C- and D-ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.
Public/Granted literature
- US20110288166A1 TRIPTOLIDE C-RING DERIVATIVES AS ANTICANCER AGENTS AND IMMUNE MODULATORS Public/Granted day:2011-11-24
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