Invention Grant
- Patent Title: Entry inhibitors of the HIV virus
- Patent Title (中): HIV病毒的进入抑制剂
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Application No.: US10571325Application Date: 2004-09-10
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Publication No.: US08268885B2Publication Date: 2012-09-18
- Inventor: Koenraad Lodewijk August Van Acker , Piet Tom Bert Paul Wigerinck , Lieve Emma Jan Michiels , Abdellah Tahri
- Applicant: Koenraad Lodewijk August Van Acker , Piet Tom Bert Paul Wigerinck , Lieve Emma Jan Michiels , Abdellah Tahri
- Applicant Address: IE Cork
- Assignee: Janssen R&D Ireland
- Current Assignee: Janssen R&D Ireland
- Current Assignee Address: IE Cork
- Agent Toni-Junell Herbert
- Priority: EP03103362 20030911
- International Application: PCT/EP2004/052139 WO 20040910
- International Announcement: WO2005/023242 WO 20050317
- Main IPC: A61K31/24
- IPC: A61K31/24 ; A61K31/22 ; A61K31/18 ; A61K31/16 ; C07C311/25 ; C07C67/02 ; C07C235/74 ; C07C235/78
Abstract:
The present invention relates to small molecules as entry inhibitors of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors with other anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS.
Public/Granted literature
- US20070066623A1 Entry inhibitors of the hiv virus Public/Granted day:2007-03-22
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