Invention Grant
- Patent Title: Use of dapsone as a neuroprotector in cerebral infarction
- Patent Title (中): 在脑梗死中使用氨苯砜作为神经保护剂
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Application No.: US10565309Application Date: 2004-03-16
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Publication No.: US08268893B2Publication Date: 2012-09-18
- Inventor: Luis Camílo Ríos Castañeda , Marina Altagracia Martínez , Juan Nader Kawachi , Jaime Kravzov Jinich
- Applicant: Luis Camílo Ríos Castañeda , Marina Altagracia Martínez , Juan Nader Kawachi , Jaime Kravzov Jinich
- Applicant Address: MX Mexico City MX Mexico City
- Assignee: Universidad Autonoma Metropolitana,Instituto Nacional de Neurologia y Neurocirurgia Manuel Velasco Suarez
- Current Assignee: Universidad Autonoma Metropolitana,Instituto Nacional de Neurologia y Neurocirurgia Manuel Velasco Suarez
- Current Assignee Address: MX Mexico City MX Mexico City
- Agency: Egbert Law Offices, PLLC
- Priority: MXPA/a/2003/006549 20030722
- International Application: PCT/MX2004/000018 WO 20040316
- International Announcement: WO2005/007239 WO 20050127
- Main IPC: A01N33/02
- IPC: A01N33/02 ; A61K31/135
Abstract:
The use of dapsone is the first effective treatment against the disabling consequences associated with cerebral infarction in patients. Dapsone was evaluated as a neuroprotector in the cerebral infarction model produced by the occlusion of the middle cerebral artery in rats and in patients suffering from acute cerebral infarction caused by thromboembolism. In both studies, dapsone displayed a reduction of between 70 and 90% in the adverse effects which occur as a consequence of the infarction.
Public/Granted literature
- US20100063159A1 Use of dapsone as a neuroprotector in cerebral infarction Public/Granted day:2010-03-11
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