Invention Grant
- Patent Title: Humanized anti-C5aR antibodies
- Patent Title (中): 人源化抗C5aR抗体
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Application No.: US12866009Application Date: 2009-02-19
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Publication No.: US08268972B2Publication Date: 2012-09-18
- Inventor: Peter Whitfeld , David Zahra , Charles Mackay
- Applicant: Peter Whitfeld , David Zahra , Charles Mackay
- Applicant Address: AU Darlinghurst
- Assignee: G2 Inflammation Pty Ltd
- Current Assignee: G2 Inflammation Pty Ltd
- Current Assignee Address: AU Darlinghurst
- Agency: Bozicevic, Field & Francis LLP
- Agent Carol L. Francis
- International Application: PCT/AU2009/000184 WO 20090219
- International Announcement: WO2009/103113 WO 20090827
- Main IPC: C07K16/28
- IPC: C07K16/28
Abstract:
The present invention is directed to humanized antibodies which bind the human C5a receptor and their use as therapeutic and diagnostic agents. The present invention is further directed toward nucleic acid sequences which encode said humanized antibodies, and their expression in recombinant host cells. In particular, the present invention is directed towards humanized antibodies derived from murine antibody 7F3 which specifically binds to the human C5a receptor.
Public/Granted literature
- US20110190477A1 Humanized Anti-C5aR Antibodies Public/Granted day:2011-08-04
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