Invention Grant
US08269003B2 Stable crystal form of imatinib mesylate and process for the preparation thereof
有权
甲磺酸伊马替尼的稳定晶体形式及其制备方法
- Patent Title: Stable crystal form of imatinib mesylate and process for the preparation thereof
- Patent Title (中): 甲磺酸伊马替尼的稳定晶体形式及其制备方法
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Application No.: US11574642Application Date: 2005-09-02
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Publication No.: US08269003B2Publication Date: 2012-09-18
- Inventor: Srinivas Laxminarayan Pathi , Revikumar Puppala , Rajendra Narayanrao Kankan , Dharmaraj Ramachandra Rao
- Applicant: Srinivas Laxminarayan Pathi , Revikumar Puppala , Rajendra Narayanrao Kankan , Dharmaraj Ramachandra Rao
- Applicant Address: IN Mumbai
- Assignee: CIPLA Limited
- Current Assignee: CIPLA Limited
- Current Assignee Address: IN Mumbai
- Agency: Conley Rose, P.C.
- Agent Rodney B. Carroll
- Priority: IN951/MUM/2004 20040902
- International Application: PCT/GB2005/003392 WO 20050902
- International Announcement: WO2006/024863 WO 20060309
- Main IPC: C07D411/00
- IPC: C07D411/00
Abstract:
The invention relates to imatinib for use in tumor therapy. This invention describes a stable, non hygroscopic alpha crystalline form of methane sulfonic acid addition salt of 4-(4-methyl piperazin-1-yl methyl)-N-[4-methyl-3-(4-pyridin-3-yl)-pyrimidin-2-yl amino) phenyl]-benzamide (imatinib mesylate) having the general structural formula A process for the preparation of the crystalline form is also described.
Public/Granted literature
- US20070265288A1 Stable Crystal Form of Imatinib Mesylate and Process for the Preparation Thereof Public/Granted day:2007-11-15
Information query
