Invention Grant
- Patent Title: Substituted pyrazole inhibitors of c-Met protein kinase
- Patent Title (中): c-Met蛋白激酶的取代吡唑抑制剂
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Application No.: US12788715Application Date: 2010-05-27
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Publication No.: US08269013B2Publication Date: 2012-09-18
- Inventor: Pan Li , Nathan Waal , Steven Ronkin , Qing Tang , David Lauffer
- Applicant: Pan Li , Nathan Waal , Steven Ronkin , Qing Tang , David Lauffer
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Daniel A. Pearson
- Main IPC: C07D215/12
- IPC: C07D215/12 ; A61K31/47
Abstract:
The present invention relates to compounds of formula I, which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula I and methods of using the compositions in the treatment of proliferative disorders.
Public/Granted literature
- US20100305155A1 SUBSTITUTED PYRAZOLE INHIBITORS OF C-MET PROTEIN KINASE Public/Granted day:2010-12-02
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