Invention Grant
- Patent Title: C-nitroso-derived nitroxyl donors
- Patent Title (中): C-亚硝基衍生的硝酰基供体
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Application No.: US13177036Application Date: 2011-07-06
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Publication No.: US08269034B2Publication Date: 2012-09-18
- Inventor: S. Bruce King
- Applicant: S. Bruce King
- Applicant Address: US NC Winston-Salem
- Assignee: Wake Forest University Health Sciences
- Current Assignee: Wake Forest University Health Sciences
- Current Assignee Address: US NC Winston-Salem
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: C07C69/76
- IPC: C07C69/76 ; C07C207/00 ; A61K31/235 ; A61K31/04
Abstract:
Active compounds of Formula I are described: wherein: R1 and R2 are each independently C1-C4 alkyl; or R1 and R2 together form a C2-C7 alkylene chain; and Z is a non-steroidal anti-inflammatory drug (NSAID); along with pharmaceutically acceptable salts and prodrug thereof, and methods of using the same.
Public/Granted literature
- US20110263674A1 C-NITROSO-DERIVED NITROXYL DONORS Public/Granted day:2011-10-27
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