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US08269047B2 Synthesis of alpha-halo enones and enals 失效
α-卤代烯酮和烯醛的合成

Synthesis of alpha-halo enones and enals
Abstract:
A method for preparing an α-halo enal or enone from an unprotected propargyl alcohol and an electrophilic halogen source catalyzed by the combination of a gold catalyst complex and a metal co-catalyst complex is disclosed. The method can be further enhanced by addition of an additive that facilitates suppression of a des-halo derivative.
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