Invention Grant
- Patent Title: Process for preparing benzazepine compounds or salts thereof
- Patent Title (中): 制备苯并氮杂化合物或其盐的方法
-
Application No.: US12064178Application Date: 2006-09-01
-
Publication No.: US08273735B2Publication Date: 2012-09-25
- Inventor: Yasuhiro Torisawa , Kaoru Abe , Yasuaki Muguruma , Shigekazu Fujita , Hidenori Ogawa , Naoto Utsumi , Masahiro Miyake
- Applicant: Yasuhiro Torisawa , Kaoru Abe , Yasuaki Muguruma , Shigekazu Fujita , Hidenori Ogawa , Naoto Utsumi , Masahiro Miyake
- Applicant Address: JP Tokyo
- Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: JP2005-254744 20050902
- International Application: PCT/JP2006/317804 WO 20060901
- International Announcement: WO2007/026971 WO 20070308
- Main IPC: C07D223/16
- IPC: C07D223/16

Abstract:
This invention provides a process for preparing benzazepine compounds of the formula (1): wherein X1 is a halogen atom, R1 and R2 are a lower alkyl group, or salts thereof as well as intermediate benzoic acid compounds in high yield and high purity on industrial scale, which are useful as an intermediate for preparing a pharmaceutically active 2,3,4,5-tetrahydro-1H-1-benzazepine compound having vasopressin antagonistic activity.
Public/Granted literature
- US20090306369A1 PROCESS FOR PREPARING BENZAZEPINE COMPOUNDS OR SALTS THEREOF Public/Granted day:2009-12-10
Information query